globe

Faster diagnosis scleroderma

Faster diagnosis scleroderma with Dino-Lite CapillaryScope

Quote-box-faster-diag-cap-1

If a patient has suspected systemic sclerosis, the Dino-Lite CapillaryScope can be used to make a quick and painless examination of the capillaries in the cuticle. Actelion Pharmaceuticals Ltd cooperates with rheumatologists to make this a generally used procedure quickly.

Actelion Pharmaceuticals Ltd is originally a Swiss biopharmaceutical company focused on the discovery, development and marketing of orphan drugs on the market. "These are medications for unresolved medical problems which in most cases involves a small group of patients," says brand manager Peter Dingeldein of the Dutch division of Actelion Pharmaceuticals Ltd. Systemic sclerosis is one of the rare diseases for which the company is providing a drug. This rare chronic disease is caused by a disordered immune system, which is why this is called an autoimmune disease. In systemic sclerosis healthy tissue gets damaged and creates connective tissue. The vasculopathy is an important characteristic of this disease, that often results in digital ulcers, painful sores on the fingers. Once patients arrive at this stage, this will have major impact on everyday life, as everyday activities, such as buttoning clothes and writing difficult.

Non-invasive investigation

Quote-box-faster-diag-cap-2Dingeldein: "There is increased attention to discover systemic sclerosis as early as possible. The idea is that the sooner you discover the disease, the better it is for the patient because the damage can be limited. If a patient is suspected of systemic sclerosis, then studying the capillaries in the cuticle can provide more information about the diagnosis. This study goes well and fast with a Dino-Lite CapillaryScope. It is a simple, non- invasive and painless test that patients can watch themselves. That is reassuring for many people."

For the examination a drop of oil is placed on the cuticle and the CapillaryScope is placed on that spot. The capillaries in the cuticle are clearly visible with the magnification of 500x and thus any abnormalities suggestive of systemic sclerosis can be examined.
In most cases, the rheumatologist can reassure the patient that there is nothing to worry about. For anomalies it is easy to make a picture or recording with the CapillaryScope to save to the patient's file. At the repeat visit, usually after six months, it can be established whether the situation has improved, remained stable or deteriorated. When a patientis diagnosed with systemic sclerosis the treatment – medication - can begin immediately.

The treatment

Endothelin is the enzyme in the body that constricts blood vessels. In diseases such as systemic sclerosis, an excessive amount of endothelinis produced that ultimately create damage to the vessel walls. Actelion Pharmaceuticals Ltd is a manufacturer of Tracleer ( the generic name is Bosentanname , ed.). This is a vasodilator drug that inhibits the action of endothelin by blocking the nerve receptors that can bind endotheline which will improve the blood flow. Tracleer does not heal, but prevents worse and helps to stabilize the patient.

This is capillaroscopy:
The investigation of the cuticle with the Dino-Lite CapillaryScope is quick and painless. Click on the link to see a movie, that shows exactly how the research process works.

Recommended / Alternative Products:

MS33W Stand

MS33WRound metal base with flexible arm and holder for the Dino-Lite. The MS33W has the possiblility to vary the height (appr. 15 mm) with a turning knob in the base.

Read More...

MS23B

MS23BThe MS23B is a desktop clamp with flexible gooseneck that can be clamped to a desktop or any other surface of up to 3cm thick.

Read More...

AM4113ZT

AM4113ZT-relatedBy using a special polarization filter, the AM4113ZT is the right choice when working with high glare materials such as plastics and metals.

Read More...

AM7013MZT

AM7013MZT-relatedThe Dino-Lite AM7013MZT has a 5 megapixel sensor for crystal clear images, even under higher magnification. The built-in adjustable polarizer reduces glare and reflection on shiny objects.

Read More...

AD4013MZTL

AD4013MZTL-relatedThis MZTL model has a long working distance, polarisation filter and a third (exchangeable) polarisation cap as well as aluminum alloy housing.

Read More...

AM4013MZTL

AM4013MZTL-relatedBy using a special polarization filter, the AM4013MZTL is the right choice when working with high glare materials such as plastics and metals. This model features an aluminum alloy housing for enhanced protection and durability and the best look and feel.

Read More...

AM4113ZTL

AM4113ZTL-relatedBy using a special polarization filter, the AM4113ZTL is the right choice when working with high glare materials such as plastics and metals.

Read More...

RK-06-AE Stand

MS36BThe Dino-Lite RK-06-AE stand is a sturdy and stable mid-range stand solution that can be used with all Dino-Lite digital microscopes. It is constructed of stainless steel and lightweight aluminum and offers precise fine-focus adjustment as well as a quick vertical release function.

Read More...

SW-F1 Footpedal

SW-F1
The SW-F1 allows you to take a picture with a simple step from your foot using the Dino-Lite or Dino-Eye digital microscopy solutions. No additional software is required, simply plug in the device into your USB port and it is ready to use.

Read More...

AD7013MZT

AD7013MZT-relatedThe Dino-Lite AD7013MZT has a 5 megapixel sensor for crystal clear images, even under higher magnification. The built-in polarizer reduces the shiny effect on reflecting materials, such as metals, plastics, jewelry, electronics etc.

Read More...